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akaturk Akademik ölçüm

Makale detayı · 2006

Isolation and Biological Activity of New and Known Diterpenoids From Sideritis stricta Boiss. & Heldr.

Dergi

Molecules
OpenAlex Açık erişim · gold SJR Q2 JCR Q3 Atıf 35 Yüzdelik 83.9% FWCI 1.18
Yıl
2006
Tür
article

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Özet

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Nine known and one new ent-kaurene diterpenoid were isolated from the acetone extract of Sideritis stricta Boiss & Heldr. The new compound, identified as ent-1 beta-hydroxy-7 alpha-acetyl-15 beta,16 beta-epoxykaurane (1) by IR, 1D and 2D NMR techniques and mass spectra, was isolated along with sideroxol (2), 7-acetyl sideroxol (3), 7-epicandicandiol (4), linearol (5), ent-7 alpha,15 beta,18-trihydroxy-kaur-16-ene (6), ent-7 alpha-acetyl,15,18-dihydroxy-kaur-16-ene (7), foliol (8), sideridiol (9) and siderol (10). The antibacterial and antifungal activities of these compounds and the whole crude acetone extract were evaluated against E. coli, S. aureus, K. pneumeonia and C. albicans.

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