Makale detayı · 2011
Is 5-fluorouracil-induced vasospasm a Kounis syndrome? A diagnostic challenge
- Yıl
- 2011
- ISSN
0267-6591- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
Cardiovascular hypersensitivity is a rare and well-documented side-effect of 5-FU (5-fluorouracil). Besides the common complications such as angina pectoris and myocardial infarction, it can also cause cardiogenic shock, and supraventricular and ventricular arrhythmias. Studies have reported that FU-induced angina most commonly occurred due to vasospasm. In our case, 9 hours after stopping the infusion of 5-FU, the patients developed symptoms and electrocardiographic (ECG) findings consistent with acute myocardial infarction. We intend to share this rare case and discuss whether this late complication after 5-FU infusion is an FU-induced vasospasm or rather an allergic reaction leading to Kounis syndrome.
Konular
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
Birincil konu Drug-Induced Adverse Reactions