The Role of Prognostic Nutritional Index in Vascular Behçet’s Syndrome

OpenAlex İngilizce

Aim: This study aimed to evaluate the levels of the Prognostic Nutritional Index (PNI) in vascular and non-vascular subtypes of Behçet’s Syndrome (BS) and its potential utility in distinguishing vascular involvement. Material and Method: This retrospective cohort study included 386 patients diagnosed with BS based on ISG criteria. Patients were categorized into vascular (n=100) and non-vascular (n=286) involvement groups. Subgroup analyses assessed organ-specific patterns of involvement. PNI values were calculated as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (/mm3). Statistical analyses were performed to compare PNI levels between subgroups. Additionally, ROC curve analysis was conducted to evaluate the discriminatory ability of PNI for detecting vascular involvement. Results: Patients with vascular involvement exhibited significantly lower mean PNI values (51.7±6.6) compared to the non-vascular group (56.9±4.4, p