Relationship Between Chronic Obstructive Pulmonary Disease and Severity of Diabetic Retinopathy

İngilizce (OpenAlex)

Purpose: The negative effects of chronic obstructive pulmonary disease (COPD) on diabetes mellitus (DM) patients are known.For these reasons, we aimed to investigate the effect of COPD on the severity of diabetic retinopathy (DRP) in patients with DM. Materials and Methods:This prospective cross-sectional study included one-hundred and fifty-six eyes of 156 patients with COPD and DM.Multinomial logistic regression models were applied to evaluate the independent relationships between DRP and COPD, including adjusting for patients' characteristics.Results: After adjustment for potential confounders, patients with low-level COPD were found to have less PDR and severe PDR.(RRR 0.01 95% CI 0.01-0.03,RRR 0.01 95% CI 0.01-0.08,respectively). Conclusion:The findings suggest an increased risk of DRP severity in patients with severe COPD.Ophthalmologists following these patients should consider the relationship between COPD and DRP.Keywords: chronic obstructive pulmonary disease; diabetes mellitus; diabetic retinopathy severity; multinomial logistic regression. 97COPD on eye tissues.COPD has been shown to reduce the functional capacity of the corneal endothelium and lower the response to surgical stress 8 .It has been shown that subfoveal choroidal thickness decreases, and retinal nerve fiber layer thickness (RNFL) change occur in COPD 9, 10 .Decreased retrobulbar blood flow, parafoveal vascular density and subfoveal choroidal thickness are other significant effects of COPD on the eye 11,12,13 .In light of these findings, the severity of DRP may be adversely affected in COPD patients.Therefore, we aimed to investigate the effect of COPD on the severity of DRP in DM patients. MATERIALS AND METHODSThis prospective cross-sectional study consists of 156 DM and COPD patients examined at the Aksaray University School of Medicine, ophthalmology department.All study procedures were conducted per the Declaration of Helsinki, and informed consent was obtained from all participants.