Makale detayı · 2017
The neutrophil-to-lymphocyte ratio as a diagnostic marker for malignant thyroid diseases
Turkish Journal of Biochemistry
- Yıl
- 2017
- ISSN
1303-829X- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
Abstract Background The neutrophil-lymphocyte ratio (NLR) is a good marker of malignant diseases. The aim of this study was to investigate NLR as a diagnostic marker of thyroid cancer in patients with malignant thyroid diseases compared to those with benign thyroid diseases. Methods Two hundred and fifty three patients were divided into two groups: benign and malignant thyroid disease patients. Malignant thyroid disease group was not sub-grouped further into differentiated and undifferentiated. The preoperative complete blood count and biochemical parameters, including NLR, were evaluated. Results The mean neutrophil count was found to be significantly higher, whereas the mean lymphocyte count was found to be significantly lower in the malignant group which includes 40 of the patients. As a result, NLR was significantly higher in the malignant group than in the benign group (p<0.001). Conclusion This is the first study to show the value of NLR as a marker for malignant thyroid diseases including all subtypes.
Konular
- Inflammatory Biomarkers in Disease Prognosis
- Thyroid Cancer Diagnosis and Treatment
- Biomarkers in Disease Mechanisms
Birincil konu Inflammatory Biomarkers in Disease Prognosis