Makale detayı · 2022
An efficient approach to access 2,5-disubstituted 1,3,4-oxadiazoles by oxidation of 2-arenoxybenzaldehyde N-acyl hydrazones with molecular iodine
- Yıl
- 2022
- ISSN
2365-6549- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
Abstract An oxidative cyclization of 2‐arenoxybenzaldehyde N‐ acyl hydrazones 3 a – o was employed to synthesize new 2,5‐disubstituted 1,3,4‐oxadiazole compounds 4 a – d, 4 f – i, 4 k – n . This method involves oxidative cyclization of 2‐arenoxybenzaldehyde N‐ acyl hydrazones 3 a – o with molecular iodine mediated catalysis in which potassium carbonate served as a base. Characterization of all the synthesized novel compounds involved, proton and carbon NMR, mass spectrometry, and CHN elemental analysis. The synthesis of novel 2,5‐disubstituted 1,3,4‐oxadiazoles may display potential to provide pharmacologically important heterocyclic compounds.
Konular
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Multicomponent Synthesis of Heterocycles
Birincil konu Synthesis and biological activity