Synthesis, electrochemical, biological and catalytical studies of half-sandwich Ru(II)-NSHC complexes bearing benzothiazol-2-ylidene

OpenAlex İngilizce

The half-sandwich ruthenium(II)-NSHC complexes ( 2a-l ) bearing benzothiazol-2-ylidene were synthesized by in situ deprotonation of N -substituted benzothiazolium salts ( 1a-l ) with Ag 2 O and of [( p -cymene)Cl 2 Ru] 2 , in dichloromethane under mild conditions. However, 1m and 1n under the same conditions gave N -coordinated Ru(II) complex ( 3 ). The structures of the compounds were elucidated by NMR, FT-IR, UV–Vis, HR-MS spectroscopic methods and elemental analysis. In addition, the structures of 2k and 3 were studied by X-ray crystallography. The electrochemical properties of the complexes were investigated. Ru(II)-NSHC complexes have been used as catalysts in the transfer hydrogenation of carbonyls to secondary alcohols in the presence i -PrOH/KOH. Additionally, the effects of structural differences arising from different alkyl groups on the nitrogen atom in the benzothiazole skeleton in Ru(II)-NSHC complexes on anticancer, antifungal and antimicrobial activity were also examined.