Makale detayı · 2025
The Diagnostic Potential of Blood Soluble Urokinase Plasminogen Activator Receptor Levels in Lung Cancer and Tuberculosis Patients
Dicle Tıp Dergisi
- Yıl
- 2025
- ISSN
1300-2945- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
Aim: The study aimed to investigate the potential role of soluble urokinase plasminogen activator receptor (SUPAR) levels in the blood and bronchoalveolar lavage (BAL) fluid for the early diagnosis of lung cancer and tuberculosis (TB). Methods: Bronchoscopy and BAL were performed on 66 patients with a prediagnosis of lung malignancy or tuberculosis. SUPAR levels were measured using the ELISA method and compared with those from 30 healthy individuals as the control group. Results: Blood SUPAR, values were 199.40 ng/L in malignancy patients, 246.09 ng/L in TB patients, and 234.60 ng/L in others. In BAL fluid, values were 56.78 ng/L in lung cancer patients, 39.24 ng/L in TB patients, and 44.00ng/L in other diseases. Significant differences were found in blood SUPAR between patients and controls (p
Konular
- Protease and Inhibitor Mechanisms
- Inflammation biomarkers and pathways
- Galectins and Cancer Biology
Birincil konu Protease and Inhibitor Mechanisms