Identification and antimicrobial susceptibilities ofEnterobacter species isolated from clinical specimenin southeastern Turkey from 2015 to 2017

İngilizce (OpenAlex)

Background/aim: Enterobacter species often colonise human gastrointestinal tract, causing various opportunistic infections.Enterobacter cloacae and Enterobacter asburiae are the most frequently isolated Enterobacter species.The aim of this research was to investigate antimicrobial resistance among Enterobacter spp.strains isolated from patients in a tertiary hospital of Southeastern Turkey.There are few publications on antibiotic resistance of Enterobacter species. Materials and methods: This retrospective study includedEnterobacter spp.strains isolated from clinical specimen sent from Dicle University Hospital clinics from 2015 to 2017.The isolates to be considered as infection agents were identified by MALDI-TOF mass spectrometry.The antimicrobial susceptibility test (AST) was carried out by semiautomated microbiology system and evaluated according to EUCAST v.8.0 criteria.Results: A total of 296 (93 in 2015, 96 in 2016, and 107 in 2017) Enterobacter spp.strains was were isolated over three-years period.The most frequently identified species was E. cloacae (240 strains, 81.1%).The highest resistance was found against aztreonam (41.8%) and ceftazidim (41.9%) while lowest resistance was against amikacin, meropenem and ciprofloxacin.Conclusion: Amikacin and meropenem were the most effective antibiotics against E. cloacae.The resistance rates of other Enterobacter strains other than E. cloacae varied according to years and species.