Carcinoid Tumors of Appendix Presenting as Acute Appendicitis

İngilizce (OpenAlex)

BACKGROUND:We aim to present the data of patients who underwent appendectomy due to acute appendicitis, and incidental carcinoid tumor was detected on pathology.METHODS: Retrospective analysis of the patient charts between January 1999 and September 2018 were performed.RESULTS: 2778 appendectomy was performed due to acute appendicitis.Appendiceal carcinoid tumor was detected in 12 (0.43%) patients.Eight patients were (66.7%) female.Median age 37.5 years (range: 21-60).The median tumor size was 0.7 cm (range: 0.1-2.5).No perforation was detected.Eleven patients underwent appendectomy, and one patient had right hemicolectomy.The median followup period was 41.5 months (range: 22-49).There were no recurrences.CONCLUSION: Appendix carcinoid tumors are quite rare, usually asymptomatic and diagnosed incidentally on histopathological examination after appendectomy.The treatment of carcinoid tumors of the appendix is directly related to the tumor size, localization, presence of lymphovascular and mesoappendix invasion, mitotic activation rate and level of Ki67.Thus, it is important to follow the histopathological results after appendectomy.The prognosis of appendix carcinoid tumors is very good if the appendix is non-perforated.Keywords: Acute appendicitis; appendectomy; carcinoid tumor.were analysed.Age, gender, symptoms, physical examination findings, follow-up times of the patients, preoperative abdominal ultrasonography findings, the indication for operation and the type of the operation were evaluated.Location of the tumor, tumor diameter, depth of invasion, histopathological cell type, mitotic activation rate and level of Ki67 of the tumor were defined. Statistical AnalysisFor statistical evaluation, descriptive analysis was used.For homogenous distributions, we used mean and standard deviation, and for heterogeneous distributions we preferred median and range. RESULTSDuring the study period, a total of 2778 patients underwent an emergency appendectomy.The patients who underwent