Hashimoto Tiroiditi Tanısı Alan Vakaların Geriye Dönük Değerlendirilmesi (A Retrospective Evaluation of the Cases Diagnosed as Hashimoto’s Thyroiditis)

İngilizce (OpenAlex)

Aim: Hashimoto’s thyroiditis (HT) is the most common cause of goiter and acquired hypothyroidism in children and adolescents in iodine-replete areas. This study was planned retrospectively in order to find out the epidemiologic, clinical and laboratory characteristics of HT in childhood. Method: One hundred and two patients with diagnosis of HT who were followed up in our clinic from 2005 to 2010 were included in the study. Results: Ninety (88.2 %) patients were girls, twelve (11.8 %) were boys and female/male ratio was 7.5/1. Mean age at diagnosis was 11.4±2.4 years (range 5.5-15.9 years) and 76 (74.5 %) patients were in puberty. Fifty percent of patients had a family history of thyroid disease, 7.8 % had another autoimmune disease. In the patients the most common complaint and sign was goiter (41.1 % and 100 % respectively). AntiTPO and antiTg were positive in 29,4 % and 16.7 % of the patients, respectively. The remainders were positive for both of them. Thyroid ultrasonography was performed in 82 patients and heterogenity and/or pseudonodule of thyroid parenchyma were/was found in 70 (85.3 %) patients. At the time of diagnosis 28 (27.5 %) patients were euthyroid, 56 (55 %) patients had subclinical, and 18 (17.5 %) patients had overt hypothyroidism. In none of the patients hyperthyroidism was not found. Conclusion: As a result, HT is mostly seen in girls especially in patients with goiter and a positive family history. As hypothyroid state affect growth and development, early diagnosis of HT is very crucial.