Makale detayı · 2023
The Impact of Vaccination with SARS-CoV-2 Vaccines on the Course of Chronic Spontaneous Urticaria
Dergi
Allergy Asthma ImmunologyISSN 1308-9234
ISSN kaydı başka bir dergiye işaret ediyor; ad YÖKSİS kaydından.
- Yıl
- 2023
- DOI
- 10.21911/aai.083
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Allergy Asthma Immunology
- Katalog eşleşmesi (ISSN) Asthma Allergy Immunology
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
Objective: Although the factors that trigger and exacerbate chronic spontaneous urticaria (CSU) are well known, there is still a lack of information about the effects of COVID-19 vaccines on CSU.This study aimed to investigate exacerbations/relapses triggered by COVID-19 vaccines in patients with CSU who are well controlled with treatment or in remission. Materials and Methods:The study included 350 CSU patients.Demographic and clinical characteristics were collected from patients' medical records.The seven-day urticaria activity score (UAS7) and urticaria control test (UCT) were evaluated separately during the onset of the disease, pre-vaccination, and post-vaccination periods.Results: The mean age was 39.89±13.30years and 74.6% of the patients were female.A total of 227 patients were vaccinated with the Pfizer/BioNTech mRNA vaccine, 67 with the Sinovac/CoronaVac inactivated vaccine, and 54 with both vaccines.Urticaria exacerbations/ relapses were observed in a total of 76 patients, and most CSU exacerbations/relapses occurred after the first dose (n=46).Median UAS7 scores increased significantly in the post-vaccination period in patients who experienced urticaria exacerbation (p<0.0001).Median UCT scores were significantly decreased due to urticaria exacerbation with vaccination (p<0.0001).Conclusion: Both mRNA and inactivated COVID-19 vaccine may lead to exacerbations or relapses in patients with CSU.Even so, exacerbations/relapses associated with COVID-19 vaccines can be easily controlled with treatments and do not preclude subsequent doses.
Konular
Atıflar
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