The Association of Vitamin D Insufficiency/Deficiency with Metabolic Syndrome, Quality of Life and Depression in Postmenopausal Women

İngilizce (OpenAlex)

Aim: This cross-sectional study aimed to assess the association of vitamin D insufficiency/deficiency with metabolic syndrome risk factors, quality of life, and depression in postmenopausal women aged 50 years and older. Materials and methods: The study was conducted with women who attended a handicraft course in Bursa Province, Turkey, in March 2019. At the initial visit, blood samples were obtained from the individuals, and the study was proceeded with 150 out of 165 participants with serum 25-hydroxyvitamin D (25(OH)D) levels lower than 30 ng/mL. At the second visit, the subjects were questioned about their general characteristics, quality of life, and depression. In addition to the questionnaire, metabolic syndrome was defined according to the diagnostic criteria of the International Diabetes Federation, and waist circumference and blood pressure measurements were made for each participant. Results: The prevalences of vitamin D insufficiency and deficiency in the participants were 21.3% and 78.7, respectively. When compared to the women with vitamin D insufficiency, those with vitamin D deficiency displayed a significantly higher metabolic syndrome prevalence (46.6% vs 18.8%), waist circumference, blood pressure, and fasting blood glucose levels, and significantly lowered high density lipoprotein cholesterol levels (P