Oxidative stress in calves with enzootic pneumonia

OpenAlex İngilizce

This study was performed to evaluate the oxidative stress in calves with enzootic pneumonia. Ninety calves that were 2?6 months old were used in this study. Ten of these calves were healthy and used as the control group, while 80 were diagnosed with enzootic pneumonia according to the clinical examinations. The biochemical results showed that total oxidant status (TOS), nitric oxide (NO), malondialdehyde (MDA), and sialic acid (SA) levels were higher in calves with enzootic pneumonia than in the control group. While there was a statistically significant increase in TOS, MDA, and SA concentrations, there was not any statistically significant change at NO levels. Furthermore, a statistically significant decrease was observed in total antioxidant status (TAS), superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) concentrations. Oxidative stress index (OSI) was calculated after TOS and TAS concentrations were obtained and it was detected to be high, but not statistically significant. In conclusion, according to these results, severe oxidative stress was detected in calves with enzootic pneumonia. These results reveal that oxidative stress may have a role and contribution in the occurrence of the disease and the obtained results might contribute to further studies. Besides, it is concluded that antioxidant supplements would be beneficial for supporting the routine treatment of the disease.