Makale detayı · 2020
Equine Adipose Tissue Derived Mesenchymal Stem Cells and Their Multilineage Differentiation
Kocatepe Veterinary Journal
- Yıl
- 2020
- ISSN
1308-1594- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
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Özet
İngilizce (OpenAlex)
Mesenchymal stem cells (MSCs) have become a potent source for cell therapy due their inherent properties of self-renewal and ability to undergo unlimited divisions in the field of regenerative medicine. In this study, equine adipose tissue stem cells (EASCs) have been evaluated on the basis of their morphology, proliferation potential and multilineage differentiation capabilities for their future usage in cell therapy. The cells were further differentiated into osteogenic and adipogenic cell lineages as well as into adipose derived neurospheres to ensure the stemness of propagated cells. In our study, we further successfully cultured the neurosphere derived cells which were cultured from neurospheres after enzymatic dissociation. The study exhibits that EASCs offer a suitable choice for cellular regenerative therapy in equines. Nonetheless, there is a still need to molecular characterization of EASCs in order to establish a standard practice in equine medicine.
Konular
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Pluripotent Stem Cells Research
Birincil konu Mesenchymal stem cell research