Makale detayı · 2024
FAVA Syndrome with Unique Synovial Localisation Mimicking Diffuse Pigmented Villonodular Synovitis
- Yıl
- 2024
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Balkan Medical Journal
- Katalog eşleşmesi (ISSN) Balkan Medical Journal
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
In 2014, Alomari et al. 1 have described a novel clinical, radiologic, and histopathologic entity known as "fibroadipose vascular anomaly (FAVA)" that comprises a fibroadipose lesion associated with venectasia and presents with pain.Since then, 143 cases have been published in the English literature as case reports or case series, spanning the ages of newborns to 35 years.Of these, only 35 cases were male.[2][3][4][5][6][7] The lesion, which is primarily found in the soft tissues of the lower extremities, was also described in the soft tissues of the upper extremities and trunk.Histologically, these intramuscular masses are composed of proliferated thin-walled, blood-filled vessels, fatty tissue, and dense perivascular fibrous tissue. 2 Despite FAVA being a sporadic lesion that is particularly associated with somatic mutations in the PIK3CA gene, the diagnosis of previously presented cases was primarily based on radiological and histopathological findings.Only a few presented cases exhibit molecular evidence of PIK3CA mutations.2,6,8
Konular
- Musculoskeletal synovial abnormalities and treatments
- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
Birincil konu Musculoskeletal synovial abnormalities and treatments