Effects of Intranasal Butorphanol-Diazepam Combination on Ultrasonographic Ocular Biometry, Tear Production, and Intraocular Pressure in Yellow-Legged Gulls

İngilizce (OpenAlex)

The aim of this study was to evaluate the effects of intranasal butorphanol-diazepam sedation on tear production, intraocular pressure (IOP), and ocular biometry in Yellowlegged Gulls (Larus michahellis).Eighteen gulls (nine juvenile, nine adult) undergoing rehabilitation were included.Measurements from the left (n=18) and right (n=18) eyes were analyzed separately for Schirmer Tear Test I (STT-I), IOP, and ultrasonographic parameters.Sedation was achieved with intranasal diazepam (8mg/kg) and butorphanol (1mg/kg).The body weights of the gulls were 670.55±35.84g for juveniles and 782.22±61.61g for adults.The sedation protocol used in this study produced statistically significant decreases (P<0.05) in juvenile animals in STT-I, anterior chamber depth (ACD), vitreous chamber depth (VCD), axial globe length (AGL), equatorial globe width (EGW) and pecten oculi length (POL).Statistically significant increases (P<0.05) were detected in lens axial height (LAH) and axial globe height (AGH).In adults, statistically significant decreases (P<0.05) were observed in central corneal thickness (CCT), ACD, and VCD while LAH, EGW and AGH showed statistically significant increases (P<0.05).Although decreases in IOP and increases in lens thickness (LT) were noted in both groups, no statistically significant differences were detected.These results indicate that intranasal butorphanol-diazepam provides reliable sedation for ophthalmic assessment in Yellow-legged Gulls without adverse effects; however, its influence on ocular parameters should be considered when interpreting measurements under sedation.