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akaturk Akademik ölçüm

Makale detayı · 2022

In vitro, in silico and Pharmaco-toxicological Efficiencies of some Triazole Derivatives on Inhibition of Digestive Enzyme Alpha-amylase

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

YÖKSİS OpenAlex Açık erişim · diamond SJR Q2 JCR Q4 Atıf 1 Yüzdelik 42.2% FWCI 0.12
Yıl
2022
ISSN
1516-8913
Tür
article

Veri kaynağı ayrımı

  • YÖKSİS YÖKSİS makale kaydı
  • OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)

Özet

İngilizce (OpenAlex)

HIGHLIGHTS T2DM is increasing rapidly in the world and this brings a constant search for drugs. Compound VII showed the strongest inhibition on α-amylase activity with low IC50 value. Compound VII, amylase inhibition activity was found to be strong on AR42J cells. Compound VII may play role an alternative and non-cytotoxic α-amylase inhibitor for T2DM.

Konular

  • Enzyme Production and Characterization
  • Enzyme function and inhibition
  • Click Chemistry and Applications

Birincil konu Enzyme Production and Characterization

Yazarlar

  1. ELİF AYAZOĞLU DEMİR
  2. AHMET ÇOLAK KARADENİZ TEKNİK ÜNİVERSİTESİ
  3. SELCEN ÇELİK UZUNER KARADENİZ TEKNİK ÜNİVERSİTESİ
  4. AHMET YAŞAR KARADENİZ TEKNİK ÜNİVERSİTESİ
  5. OLCAY BEKİRCAN
  6. Aylin Kabahasanoglu