Risk Factors For Diabetic Polyneuropathy

İngilizce (OpenAlex)

Objective: Diabetes Mellitus is one of the most common metabolic diseases. The most frequent complication of DM is diabetic polyneuropathy.Diabetic polyneuropathy is related to high mortality, morbidity, hospitalization rate and serious level of economic burden. We aimed in this study to determine the risk factors that affect DPN pathology. Method: Patients with abnormalities in the nerve conduction study constituted the polyneuropathy group, and patients without abnormalities formed the control group When the laboratuary values of the patients were analyzed, blood tests of 168 of 202 patients were reached. 117 of these patients had PNP and 51 did not have PNP. Results: In patients with PNP, glycolyzed hba1c ratio and fasting blood sugar were significantly higher than patients without PNP. (p <.001) While HDL rate was lower in patients with PNP than those without PNP (p <0.01), TG / HDL ratio was higher (p <0.05). In patients with PNP, glycolyzed urea (p <0.001) and creatinine (p <0.01) were significantly higher than those without PNP. The serum level of 25 (OH) vitamin D was significantly lower in patients with PNP than in patients without PNP (p <0.05). Ferritin was significantly higher in patients with PNP than patients without (P <0 .01). Conclusion: Knowing and preventing risk factors for diabetic polyneuropathy, we can take a new direction to our treatment approaches and take early measures. Fasting blood sugar and hba1c control, regulation of lipid profile, monitoring of vitamin d and ferritin levels are particularly necessary for protection of polyneuropathy.