Investigation of the Role of Nesfatin-1 Levels in the Evaluation of Nutrition Monitoring in the PICU

İngilizce (OpenAlex)

Introduction:Although nutrition is very effective on mortality in critically ill children, patients cannot be fed adequately.There is no suitable biomarker for enteral nutrition monitoring and management.The aim of this study; To investigate the usability of nefsatin-1 for nutritional monitoring and management in critically ill children. Methods:In the January-September 2019 period, 35 critically ill children who were hospitalized in the tertiary pediatric intensive care unit without any signs of inflammation were included in the study.Nesfatin-1, vitamin D level, prealbumin, albumin was evaluated for the study.Results: Thirty-five patients who were admitted to the pediatric intensive care unit and whose hospitalization reasons had regressed were evaluated.The mean nesfatin-1 values of the patients were measured as 9.95±0.78ng/mL (4.25-18.93ng/mL).There was a negative and low (r=-0.214)relationship between target calorie intake and nesfatin-1, a positive and low (r=0.172)relationship with prealbumin, and a positive and high relationship with vitamin D (r=0.529).Similar relationships were determined between the weight change ratio and nesfatin-1 (r=-0.266),prealbumin (r=0.154) and vitamin D (r=0.337). Conclusion:Based on the study findings, it was concluded that serum nefsatin-1, albumin and prealbumin are not appropriate indicators for nutritional monitoring and management in critically ill children.