Microbiological Analysis of Pseudomonas Aeruginosa and Staphylococcus Aureus Strains Isolated From Chronic Wounds

İngilizce (OpenAlex)

Background: Wounds are classified as acute and chronic according to their clinical course. Although chronic wounds are rare, they can lead to death due to delays in healing. In both types of wounds, colonization with gram positive and gram negative bacteria can be observed. The diagnosis of microorganisms and antibiotic susceptibility profiles are known to be very important in treatment. Material and Method: Swabs were taken from patients diagnosed with chronic wounds in our hospital. The samples were subjected to isolation and identification methods for microbiological analysis. Phenotypic antibiotic susceptibility analysis of each isolate was performed. Target gene analysis was performed for Staphylococcus aureus and Pseudomonas aeruginosa strains. Discussion: Acute and chronic wound wounds can cause significant health problems and even death. Especially chronic wounds may cause sepsis due to their delayed healing. Wounds can be colonized with hospital and community-acquired bacteria. Wounds can also be colonized with both gram-positive and gram-negative bacteria. In our study, colonization with S. aureus and P. aeruginosa was more common. Males were more susceptible than females. Conclusion: The most frequently isolated strains from patients with chronic wounds were S. aureus and P. aeruginosa. These strains were found to have multiple drug resistance. It was observed that strains with resistance genes posed a serious risk. A good understanding of the profiles of hospital and community-acquired wounds is very important in terms of establishing the correct treatment processes.