Investigation of Serum Brain-derived neurotrophic factor, Leptin and Ghrelin Levels in Missed Abortion: A Prospective Study

İngilizce (OpenAlex)

Objective: The aim of this study is to investigate the relationship between serum leptin, ghrelin and Brain-derived neurotrophic factor (BDNF) in missed abortion. Method: 34 pregnant women diagnosed with missed abortion and 30 healthy pregnant women were included in this study. The women included in the study were between the ages of 19 and 42. Women in the first and second trimesters were selected in the control and study groups. Pregnant women who did not have a fetal heartbeat in the first 20th week of pregnancy were considered as missed abortion. The serum leptin, ghrelin and BDNF levels of these patients were compared with the serum leptin, ghrelin and BDNF levels of healthy pregnant women with the same gestational age between the two groups. Results: The median [IQR] serum level of Ghrelin was significantly higher in woman with missed abortion compared to the healthy controls (807.17 [IQR, 540.93 – 1385.61] vs. 267.14 [IQR, 211.63 – 360.65], U=961, p