Makale detayı · 2014
How Do You Feel when You Cant Feel Your Body? Interoception, Functional Connectivity and Emotional Processing in Depersonalization-Derealization Disorder
- Yıl
- 2014
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı PLoS ONE
- Katalog eşleşmesi (ISSN) PLOS ONE
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
Depersonalization-Derealization Disorder (DD) typically manifests as a disruption of body self-awareness. Interoception -defined as the cognitive processing of body signals- has been extensively considered as a key processing for body self-awareness. In consequence, the purpose of this study was to investigate whether there are systematic differences in interoception between a patient with DD and controls that might explain the disembodiment symptoms suffered in this disease. To assess interoception, we utilized a heartbeat detection task and measures of functional connectivity derived from fMRI networks in interoceptive/exteroceptivo/mind-wandering states. Additionally, we evaluated empathic abilities to test the association between interoception and emotional experience. The results showed patient's impaired performance in the heartbeat detection task when compared to controls. Furthermore, regarding functional connectivity, we found a lower global brain connectivity of the patient relative to controls only in the interoceptive state. He also presented a particular pattern of impairments in affective empathy. To our knowledge, this is the first experimental research that assesses the relationship between interoception and DD combining behavioral and neurobiological measures. Our results suggest that altered neural mechanisms and cognitive processes regarding body signaling might be engaged in DD phenomenology. Moreover, our study contributes experimental data to the comprehension of brain-body interactions and the emergence of self-awareness and emotional feelings.
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Atıflar
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137 atıf
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Yerel katalogda bu makaleye atıf yapan 22 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
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- Attention, in and Out: Scalp-Level and Intracranial EEG Correlates of Interoception and Exteroception 2017
- The inner world of overactive monitoring: neural markers of interoception in obsessive–compulsive disorder 2017
- The roles of interoceptive sensitivity and metacognitive interoception in panic 2015
- How words ripple through bilingual hands: Motor-language coupling during L1 and L2 writing 2020
- Heart evoked potential triggers brain responses to natural affective scenes: A preliminary study 2015
- Integration of Intention and Outcome for Moral Judgment in Frontotemporal Dementia: Brain Structural Signatures 2016
- Altered neural signatures of interoception in multiple sclerosis 2018
- Variability in functional brain networks predicts expertise during action observation 2017