Comparison of hyperbaric oxygen, ozone, and dexpanthenol therapies in rats with acute lung injury

OpenAlex İngilizce

BACKGROUND AND AIM: Acute respiratory distress syndrome (ARDS) is a fatal disease presenting with respiratory failure. Patients with ARDS account for a considerable portion of patients staying in the intensive care unit (ICU). Therefore, advances in the treatment of these patients are of great importance. Direct or indirect injury to the lung initiates an inflammatory process. This results in impaired integrity of the alveolar-capillary membrane, pulmonary edema, and severe hypoxia. The present study compared hyperbaric oxygen (HBO), ozone, and dexpanthenol therapies administered to rats with experimentally induced ARDS, as well as the efficacy of these therapies.