Incidence of and risk factors for hyperoxemia among potentially critically ill patients treated in the wards: a retrospective study

İngilizce (OpenAlex)

Background/aim: The literature shows a link between hyperoxemia and poor outcomes, whereas this association remains unclear in hospital wards. This study aims to determine the incidence of hyperoxemia in hospital wards and its risk factors. Materials and methods: < 120 mmHg) and hyperoxemia. Results: The incidence of hyperoxemia was 42.2%. Patients with hyperoxemia had longer hospital stays and higher intensive care unit admission rates than those with normoxemia. Partial pressure of carbon dioxide < 30 mmHg (OR, 1.61; 95% CI, 1.16-2.25; p = 0.005), hemoglobin ≤ 10.3 g/dL (OR, 1.33; 95% CI, 1.01-1.75; p = 0.044), positive pressure ventilation (OR, 1.73; 95% CI, 1.09-2.74; p = 0.021), fraction of inspired oxygen ≥ 50% (OR, 1.71; 95% CI, 1.10-2.65; p = 0.018), type IV respiratory failure (OR, 1.62; 95% CI, 1.05-2.51; p = 0.030), and receiving treatment on surgical units (OR, 1.47; 95% CI, 1.02-2.12; p = 0.038) were independently associated with hyperoxemia. Charlson comorbidity index > 6 (OR, 0.64; 95% CI, 0.49-0.85; p = 0.002), and chronic obstructive pulmonary disease exacerbation (OR, 0.51; 95% CI, 0.29-0.89; p = 0.017) were independently associated with normoxemia. Conclusion: Monitoring potentially critically ill patients receiving oxygen therapy in wards is essential to mitigate hyperoxemia and optimize the use of healthcare resources. Further research could focus on developing strategies to accomplish this objective.