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Makale detayı · 2025

Comparison of Anticancer Capacity of Six Grape Extracts on Cancerous Liver Cell Line

Türk Doğa ve Fen Dergisi

YÖKSİS OpenAlex Açık erişim · hybrid TR Index Atıf 0 Yüzdelik 44.6% FWCI 0.0
Yıl
2025
ISSN
2149-6366
Tür
article

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  • OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)

Özet

İngilizce (OpenAlex)

Grape is one of the most widely consumed food sources worldwide and has been under massive research for its health benefits. In this study, we used ethanolic extracts from six different grape cultivars (both white and black grapes) to test their anticancer capacity for Huh7 liver cancer cell line. The findings showed that the grape cultivar species play the role on the cytotoxicity, which was observed as biphasic dose dependent. Based on the findings and the literature, it can be claimed rather than using whole grape extracts, fractionation of the extracts is needed to isolate bioactive compounds due to the fact that flavonoids can serve as cytotoxicity and cytoprotective behaviors depending on their chemistry.

Konular

  • Phytochemicals and Antioxidant Activities
  • Horticultural and Viticultural Research
  • Pharmacological Effects of Natural Compounds

Birincil konu Phytochemicals and Antioxidant Activities

Yazarlar

  1. Laila ALFOGOHİ
  2. Oktay BIYIKLIOĞLU
  3. Serhat KARABICAK
  4. ASLI UĞURLU BAYARSLAN
  5. İDRİS YAZGAN
  6. TALİP ÇETER KASTAMONU ÜNİVERSİTESİ