Makale detayı · 2021
Evaluation of biological activities of Barbarea integrifolia and isolation of a new glucosinolate derivated compound
Dergi
Zeitschrift für Naturforschung CISSN 0939-5075
ISSN kaydı başka bir dergiye işaret ediyor; ad YÖKSİS kaydından.
- Yıl
- 2021
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Zeitschrift für Naturforschung C
- Katalog eşleşmesi (ISSN) Zeitschrift fur Naturforschung - Section C Journal of Biosciences
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
Abstract The aim of the present study is to determine the potent biological activities and carry out isolation studies onBarbarea integrifolia. The antioxidant capacity of the species was evaluated by total phenolic content, FRAP, CUPRAC, and DPPH radical scavenging activity. Anticancer activity studies were performed by MTT assay in MDA-MB-231, MCF-7, Hep3B, PC-3, A549, HCT116, L-929 cell lines. It was observed that the remaining aqueous fraction has higher total phenolic content while higher activity in the CUPRAC and FRAP assays was displayed for the methanolic extract and chloroform fraction. The extracts showed anticancer activity as compared with vincristine. It was observed that chloroform fraction has the highest anticancer activity on MCF-7 cell line, while ethyl acetate fraction has the highest anticancer activity on Hep-3B and A549 cell lines. Methanolic extract has the highest anticancer activity on HCT116 and MDA-MB-23 cell lines. The isolation studies have been performed using several chromatographic methods. The chemical structures of compounds have been identified by means of1H NMR,13C NMR, 2D-NMR, and MS. Five major compounds, one steroid (β-Sitosterol), one phenolic acid (Rosmarinic acid), one flavonol heteroside (kaempferol 7-O-α-l-rhamnoside-3-O-β-d-(2-O-β-d-glucosyl)-β-d-glucoside), and two glucosinolates (Gluconasturtiin, Gluconasturtiin choline salt) have been isolated.
Konular
Atıflar
OpenAlex cited_by_count. WoS veya Scopus atıf sayısı değildir; o kaynaklar için ayrı kolon yoktur.
5 atıf
OpenAlex cited_by_count (önbellek / veritabanı)
Yerel katalogda bu makaleye atıf yapan 12 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
- Isolation of the major compounds and determination of biological activities of the underground parts of Trachystemon orientalis 2025
- Isolation of the major compounds and determination of biological activities of the underground parts of Trachystemon orientalis 2025
- Isolation of the major compounds and determination of biological activities of the underground parts of Trachystemon orientalis 2024
- Isolation of the Major Compounds and Determination of Biological Activities in the Underground Parts of Trachystemon orientalis D.Don 2024
- The potential of Barbarea species in the management of obesity, hyperlipidemia, and diabetes 2026
- Bio-activity guided isolation of 1,5-dicaffeoyl quinic acid from Cirsium species and investigation of their therapeutic potency on melanoma through in vitro and in silico approaches 2025
- Bio-activity guided isolation of 1,5-dicaffeoyl quinic acid from Cirsium species and investigation of their therapeutic potency on melanoma through in vitro and in silico approaches 2025
- Bio-activity guided isolation of 1,5-dicaffeoyl quinic acid from Cirsium species and investigation of their therapeutic potency on melanoma through in vitro and in silico approaches 2025
- Bio-activity guided isolation of 1,5-dicaffeoyl quinic acid from Cirsium species and investigation of their therapeutic potency on melanoma through in vitro and in silico approaches 2025
- Bio-activity guided isolation of 1,5-dicaffeoyl quinic acid from Cirsium species and investigation of their therapeutic potency on melanoma through in vitro and in silico approaches 2025