Makale detayı · 2022
Quinoline-fused both non-peripheral and peripheral Zn-II and Mg-II phthalocyanines: Anti-cholinesterase, anti-alpha-glucosidase, DNA nuclease, antioxidant activities, and in silico studies
- Yıl
- 2022
- DOI
- 10.1002/aoc.6696
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Applied Organometallic Chemistry
- Katalog eşleşmesi (ISSN) Applied Organometallic Chemistry
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
Quinoline‐fused ZnII(ZnPcp/ZnPcnp) and MgII(MgPcp/MgPcnp) phthalocyanines with four 4‐methylquinolin‐2‐ol (1) at non‐peripheral or peripheral positions of the phthalocyanine core have been synthesized via cyclotetramerization of phthalonitrile derivatives (CNp/CNnp) in the presence of zinc (II) and magnesium (II) metal ions in this study. After synthesis and characterization processes, anti‐cholinesterase, anti‐α‐glucosidase, DNA nuclease, antioxidant activities, and in silico calculations of both peripheral and non‐peripheral ZnIIand MgIIphthalocyanines were investigated. The inhibitory effects of metallated phthalocyanines on acetylcholinesterase, butyrylcholinesterase, and α‐glucosidase enzymes were tested by spectrophotometric method. Theoretical methods are used to compare both the chemical and biological activities of the studied phthalonitrile derivatives and metallated phthalocyanine compounds.
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Atıflar
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Yerel katalogda bu makaleye atıf yapan 28 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
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