Makale detayı · 2011
THE RELATIONSHIP BETWEEN DIABETIC RETINOPATHY AND SERUM LEVELS OF ISCHEMIA MODIFIED ALBUMIN AND MALONDIALDEHYDE
- Yıl
- 2011
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Retina
- Katalog eşleşmesi (ISSN) Retina
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
PURPOSE: To establish the correlation between ischemia-modified albumin (IMA) and malondialdehyde (MDA) and the development of diabetic retinopathy (DRP) in patients with diabetes mellitus. METHODS: Seventy Type 2 diabetic patients, 35 with DRP, and 36 healthy controls were enrolled in this study. Serum IMA and MDA levels were compared statistically. Receiver operating characteristic curve analysis was also performed to calculate the value of IMA and MDA in distinguishing DRP. RESULTS: Mean serum IMA levels were 0.658 ± 0.128 absorbance units in the non-DRP group, compared with 0.767 ± 0.074 absorbance units in the DRP group and 0.619 ± 0.044 absorbance units in the control group. Mean serum MDA levels were 0.325 ± 0.172 nmol/mL, 0.244 ± 0.152 nmol/mL, and 0.178 ± 0.131 nmol/mL, respectively. The differences in IMA and MDA levels were statistically significant for all groups (P < 0.05 for all). The areas under the receiver operating characteristic curves for the determination of DRP in diabetic patients were 0.789 (95% confidence interval, 0.682-0.896) for IMA and 0.3 (95% confidence interval, 0.175-0.426) for MDA. CONCLUSION: Both serum IMA and serum MDA levels were higher in the diabetic patients compared with the control group. In particular, the high sensitivity of IMA toward DRP showed that it reflected retinal vascular complication better than MDA. Ischemia-modified albumin may be a useful marker in monitoring the risk of DRP development.
Konular
Atıflar
OpenAlex cited_by_count. WoS veya Scopus atıf sayısı değildir; o kaynaklar için ayrı kolon yoktur.
47 atıf
OpenAlex cited_by_count (önbellek / veritabanı)
Yerel katalogda bu makaleye atıf yapan 36 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
- The significance of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in patients with different stages of diabetes mellitus 2018
- Evaluation of thiol/disulphide homeostasis as a novel predictor testing tool of early pregnancy viability 2018
- Pulsatile ocular blood flow changes after panretinal photocoagulation treatment in patients with proliferative diabetic retinopathy 2014
- The Association between Diabetic Retinopathy and Levels of Ischemia Modified Albumin Total Thiol Total Antioxidant Capacity and Total Oxidative Stress in Serum and Aqueous Humor 2014
- The Association between Diabetic Retinopathy and Levels of Ischemia Modified Albumin Total Thiol Total Antioxidant Capacity and Total Oxidative Stress in Serum and Aqueous Humor 2014
- Serum Anti-carbonic Anhydrase Antibodies and Oxidant–Antioxidant Balance in Patients with Acute Anterior Uveitis 2014
- Serum Anti carbonic Anhydrase Antibodies and Oxidant Antioxidant Balance in Patients with Acute Anterior Uveitis 2014
- Serum Anti carbonic Anhydrase Antibodies and Oxidant Antioxidant Balance in Patients with Acute Anterior Uveitis 2014
- Serum Anti carbonic Anhydrase Antibodies and Oxidant Antioxidant Balance in Patients with Acute Anterior Uveitis 2013
- Ischemia modified albumin IMA A novel marker of vascular involvement in Behçet s disease 2015