Makale detayı · 2018
Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride
Journal of Biomedical Materials Research Part B: Applied Biomaterials
- Yıl
- 2018
- ISSN
1552-4973- Tür
- article
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Özet
İngilizce (OpenAlex)
Hydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN). h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300°C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300°C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic β-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300°C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2384-2392, 2018.
Konular
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Graphene and Nanomaterials Applications
Birincil konu Bone Tissue Engineering Materials