Erkek yaşı sperm parametrelerini etkiliyor mu? Türk popülasyonuna ait ilk seri

Türkçe

OBJECTIVE:The aim of the study is to investigate the relationship between father age and semen parameters (concentration, motility, progressive motility, morphology, acrosomal index, semen volume) in 1402 semen samples obtained for infertility research and to contribute to the investigation of the possible effect of father age on infertility. MATRERIAL and METHODS:In our study, 1402 patients who applied to the IVF Center of Istanbul Florence Nightingale Hospital between January 2017 and May 2019 were examined.Semen samples were evaluated according to WHO criteria.Samples were divided into two groups as 40 and over 40 years.Sperm concentration (miles/mL), total motility (%), progressive motility (%), normal morphology (%) and acrosomal index (%) were compared in two groups.RESULTS: There was no statistically significant difference between total motility, progressive motility, morphology and acrosome index parameters when the two groups were compared (p>0.05).However, sperm concentration was found to be statistically significant in the group over 40 years of age (p<0.05). CONCLUSION:Although it is clear that advanced maternal age affects infertility, the relationship between advanced paternal age and infertility continues to be investigated.Our study includes the largest population from Turkey in this regard.Our results show that, with advanced age, sperm concentration increases with male age, while other parameters do not change.However, further investigations at genetic and biochemical levels are needed to investigate the relationship between advanced age and infertility.