Makale detayı · 2014
The present and future disease burden of hepatitis C virus (HCV) infection with today’xxs treatment paradigm
- Yıl
- 2014
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı JOURNAL OF VIRAL HEPATITIS
- Katalog eşleşmesi (ISSN) Journal of Viral Hepatitis
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
The number of hepatitis C virus (HCV) infections is projected to decline while those with advanced liver disease will increase. A modeling approach was used to forecast two treatment scenarios: (i) the impact of increased treatment efficacy while keeping the number of treated patients constant and (ii) increasing efficacy and treatment rate. This analysis suggests that successful diagnosis and treatment of a small proportion of patients can contribute significantly to the reduction of disease burden in the countries studied. The largest reduction in HCV-related morbidity and mortality occurs when increased treatment is combined with higher efficacy therapies, generally in combination with increased diagnosis. With a treatment rate of approximately 10%, this analysis suggests it is possible to achieve elimination of HCV (defined as a >90% decline in total infections by 2030). However, for most countries presented, this will require a 3-5 fold increase in diagnosis and/or treatment. Thus, building the public health and clinical provider capacity for improved diagnosis and treatment will be critical.
Konular
Atıflar
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182 atıf
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Yerel katalogda bu makaleye atıf yapan 8 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
- The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm 2014
- Historical epidemiology of hepatitis C virus (HCV) in selected countries 2014
- Nonalcoholic fatty liver disease: Diagnosis, pathogenesis, and management 2014
- Treatment of HCV infection with direct-acting antiviralagents. Real life experiences from the Euro-Asian region 2020
- Treatment of HCV infection with direct-acting antiviral agents. Real life experiences from the Euro-Asian region 2020
- Can family physicians have a role in eradication of hepatitis c infection? 2020
- Can family physicians have a role in eradication of hepatitis C infection? 2020
- Can family physicians have a role in eradication of hepatitis c infection? 2020