Makale detayı · 2009
The Automation of Science
- Yıl
- 2009
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Science
- Katalog eşleşmesi (ISSN) Science
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
The basis of science is the hypothetico-deductive method and the recording of experiments in sufficient detail to enable reproducibility. We report the development of Robot Scientist "Adam," which advances the automation of both. Adam has autonomously generated functional genomics hypotheses about the yeast Saccharomyces cerevisiae and experimentally tested these hypotheses by using laboratory automation. We have confirmed Adam's conclusions through manual experiments. To describe Adam's research, we have developed an ontology and logical language. The resulting formalization involves over 10,000 different research units in a nested treelike structure, 10 levels deep, that relates the 6.6 million biomass measurements to their logical description. This formalization describes how a machine contributed to scientific knowledge.
Konular
Atıflar
OpenAlex cited_by_count. WoS veya Scopus atıf sayısı değildir; o kaynaklar için ayrı kolon yoktur.
653 atıf
OpenAlex cited_by_count (önbellek / veritabanı)
Yerel katalogda bu makaleye atıf yapan 7 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
- Further developments towards a genome scale metabolic model of yeast 2010
- The Robot Scientist Adam 2009
- Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast 2011
- Yeast based automated high throughput screens to identify anti parasitic lead compounds 2013
- Yeast Systems Biology 2012
- Hypothesis-Driven Simulation Experiments with an Extension to SED-ML 2022
- Constraint-based optimisation tools for semi-automated refinement of genome-scale yeast metabolic models 2010