The efficacy of multiparametric prostate magnetic resonance imaging in the diagnosis and treatment of prostate cancer

OpenAlex İngilizce

Aim: To investigate the accuracy of multiparametric prostate magnetic resonance imaging (mpMRI) in determining the diagnosis and treatment options of prostate cancer (PCa), and its pathology correlation.Methods: Between October 2017 and January 2018, 73 patients were subjected to an mpMRI at our clinic.Of these patients, 11 were radical prostatectomy (RP) after treatment, and four were postradiation therapy (RT) follow-up.The remaining 58 patients were assigned to the PSA elevation and / or positive digital rectal examination (DRE) patient group in this study and their outcomes were evaluated.Results: Of the 58 patients included in the study, 13 were found to have a PI-RADS 5 on mpMRI and in 9 (90%) of 10 patients undergoing simultaneous biopsy, PCa was detected.The biopsy results of all cases evaluated as PI-RADS 1 were benign.All of the patients who were ISUP 3 and above had a PI-RADS 5. Patients with a PI-RADS score of 4 and above being ISUP 2 and above was statistically significant (p=0.011).A case had undergone a previous radical prostatectomy assessment revealed that tPSA increased to 2 ng/ml during the follow-up, and so RT was added to the treatment; although LAP was identified in the left iliac region on an mpMRI performed upon the continued increase of tPSA.During the follow-ups of the patient who had regional RT, the tPSA dropped below 0.01 ng/ml. Conclusion:The results of our study show that mpMRI can gain a new and important place in urology due to the guidance it provides in biopsies, facilitating targeted biopsy, its effectiveness in determining treatment modalities and its importance in post-PCa treatment follow-ups.