Investigation (In-Vitro) of Antiproliferative Properties of Pseudopediastrum boryanum (Turpin) E. Hegewald Extracts in Various Cancer Cell Lines

OpenAlex İngilizce

In this study, antiproliferative effects of Pseudopediastrum boryanum isolated and cultured from Tokat Yeşilırmak River benthic habitats were investigated with in-vitro experiments. Anticancer activity tests of algae extracts were tested in cancer cell lines using the BrdU cell proliferation ELISA method. Vero (African Green Monkey Kidney Tumour Cells) and HeLa (Human Uterine Carcinoma Cells) were examined in concentrations of 100, 250 and 500 µg/ml. As a result of antiproliferative tests, P. boryanum was found to have effective anti-cancer properties. P. boryanum extract concentrations of 250 and 500 µg/ml had a significant cytotoxic effect on Vero and HeLa cell lines after 24 hours. According to the results, P. boryanum is estimated to be a good option for quantitative pharmaceutical analyses and could be evaluated in the pharmaceutical industry.