Makale detayı · 2007
Urinary Epidermal and Insulin Like Growth Factor Excretion in Autistic Children
YÖKSİS
OpenAlex
SJR Q2
JCR Q3
Atıf 23
Yüzdelik 54.8%
FWCI 0.26
- Yıl
- 2007
- ISSN
0174-304X- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
İngilizce (OpenAlex)
Growth factors have been implicated in the pathogenesis of autism. We have investigated daily urinary excretion of insulin-like growth factor-1 (IGF-1), epidermal growth factor, and insulin-like growth factor binding protein-3 in autistic children (n=34, age 2-5 years) and age-matched control children (n=29). The mean urinary IGF-1 level was lower in the autism group than the control group (p=0.03). Height was normal. These findings suggest altered IGF-1 metabolism in young autistic children. The cause-effect relationship should be examined by longitudinal studies and insulin-like growth factor provocation tests.
Konular
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Child Nutrition and Feeding Issues
Birincil konu Autism Spectrum Disorder Research