Assessment of in vitro Antibacterial Activity and Cytotoxicity Effect of Nigella sativa Oil.

OpenAlex İngilizce

BACKGROUND: cytotoxicity is rarely investigated, is a proper and powerful candidate for treatment of methicillin-resistant isolates. OBJECTIVES: oil. MATERIALS AND METHODS: oil on the proliferation of gingival fibroblasts were evaluated. RESULTS: were between <0.25 μg/mL and 1.0 μg/mL. Compared to the control group, there was no cytotoxic effect on the proliferation of the gingival fibroblasts. CONCLUSION: . SUMMARY: ATCC: American Type Culture Collection; CLSI: Clinical and Laboratory Standards Institute; CoNS: Coagulase-negative Staphylococci; DMEM: Dulbecco's modified Eagle's medium; DMSO: Dimethyl sulfoxide; FBS: Fetal bovine serum; HGF: Human gingival fibroblast; MIC: Minimal inhibitory concentration; MRCoNS: Methicillin-resistant CoNS; MRSA: Methicillin-resistant S. aureus.