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akaturk Akademik ölçüm

Makale detayı · 2024

Recurrent simultaneous central nervous system demyelination with possible peripheral demyelination / nodopathy in a seronegative patient

Dergi

Ideggyógyászati szemle

ISSN 0019-1442

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YÖKSİS OpenAlex SJR Q4 JCR Q4 Atıf 0 Yüzdelik 21.9% FWCI 0.0
Yıl
2024
Tür
article

Veri kaynağı ayrımı

  • YÖKSİS YÖKSİS makale kaydı
  • YÖKSİS dergi adı Ideggyógyászati szemle
  • Katalog eşleşmesi (ISSN) Ideggyogyaszati Szemle
  • OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)

Özet

OpenAlex · İngilizce

Combined central and peripheral demyelination (CCPD) is a rare disease entity. Onset with the simultaneous central nervous system (CNS) and peripheral nervous system (PNS) involvement and its recurrence are exceptional. Anti-neurofascin antibodies have been shown to be present in up to 70% of cases, yet seronegative patients also exist. We present a case of seronegative recurrent CCPD. The PNS involvement was compatible with two episodes of recurrent Guillain-Barre syndrome (GBS), whereas the CNS involvement pattern was not typical for either multiple sclerosis (MS) or acute disseminated encephalomyelitis. The prognosis was excellent with pulse methylprednisolone, intravenous immunoglobulin, and plasmapheresis. This case highlights the varied clinical presentations of CCPD, extending beyond the realms of MS and chronic inflammatory demyelinating polyneuropathy, and underscores the potential for relapse. Importantly, to the best of our knowledge, this represents the inaugural instance of CCPD featuring PNS involvement in the form of recurrent GBS.

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Yazarlar

  1. BERİN İNAN
  2. CAN EBRU KURT
  3. FATMA GÖKÇEM YILDIZ SARIKAYA
  4. RAHŞAN GÖÇMEN
  5. ÇAĞRI MESUT TEMUÇİN
  6. MERYEM ASLI TUNCER
  7. MEHMET ERSİN TAN
  8. SEVİM ERDEM ÖZDAMAR HACETTEPE ÜNİVERSİTESİ