Makale detayı · 2019
Microvawe assisted synthesis of N-(methyl and methoxy) benzylidene-4-fluoroaniline derivatives and their carbonic anhydrase I and II inhibition properties
- Yıl
- 2019
- Tür
- article
Veri kaynağı ayrımı
- YÖKSİS YÖKSİS makale kaydı
- YÖKSİS dergi adı Organic Communications
- Katalog eşleşmesi (ISSN) Organic Communications
- OpenAlex OpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
OpenAlex · İngilizce
IIn this study, some Schiff base derivatives (6a-f) were synthesized using a microwave method. The synthesized compounds were characterized by 1D, 2D NMR and mass spectral data. Their inhibitory effects were studied on carbonic anhydrase isozymes (hCA I and II), purified from human erythrocyte cells by Sepharose-4B-L-tyrosine-sulfanilamide affinity chromatography and the compounds N-3-Methylbenzylidene-4-fluoroaniline (6b), N-4-Methylbenzylidene-4-fluoroaniline (6c), N-2-Methoxybenzylidene-4-fluoroaniline (6d) showed moderate activity on hCAII in the range of IC50 values.
Konular
Atıflar
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5 atıf
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Yerel katalogda bu makaleye atıf yapan 5 yayın (OpenAlex referans eşleşmesi; tam dünya listesi değildir).
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