Makale detayı · 2017 · article
Efficacy of β-Lactam/β-Lactamase Inhibitor Combinations for the Treatment of Bloodstream Infection Due to Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in Hematological Patients with Neutropenia
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- YÖKSİSYÖKSİS makale kaydı
- YÖKSİS dergi adıAntimicrobial Agents and Chemotherapy
- Katalog eşleşmesi (ISSN)Antimicrobial Agents and Chemotherapy
- OpenAlexOpenAlex zenginleştirmesi (özet, atıf, konular)
Özet
β-Lactam/β-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum-β-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem-sparing alternatives for the treatment of BSI due to ESBLs in these patients.
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